##### 1.3.2.1.3 Guidelines Compliance Obligation
In all cases, the CA MUST contractually obligate each Affiliate, RA, subcontractor, and Enterprise RA to comply with all applicable requirements in these Requirements and to perform them as required of the CA itself. The CA SHALL enforce these obligations and internally audit each Affiliate's, RA's, subcontractor's, and Enterprise RA's compliance with these Requirements on an annual basis.